PTCE Exam Dumps - Pharmacy Technician Certification (CPhT) Exam

Chemotherapy drugs (e.g., methotrexate, cisplatin)arehigh-alertdue to theirtoxicity, risk of overdose, and narrow therapeutic index.

📌Reference:ISMP High-Alert Medication List, PTCE Study Materials.

Phenobarbital is abarbiturateused forseizure control, sedation, and epilepsy management. It is commercially available in both:

Oral tablet form(commonly used for long-term seizure control).

Injectable solution form(used in hospital settings for status epilepticus and acute seizure episodes).

B. Paroxetine❌→Available only as oral tablets and oral suspension.

C. Pioglitazone❌→Available only as oral tablets (for diabetes management).

D. Pramipexole❌→Available only as oral tablets (for Parkinson’s disease and restless legs syndrome).

FDA Drug Labeling Database– ListsPhenobarbital as available in oral and injection forms.

American Society of Health-System Pharmacists (ASHP) Drug Database– Confirmsinjectable and oral availability of Phenobarbital.

PTCB PTCE Exam Content Outline– Covers medication dosage forms and routes of administration.

Why Not the Other Options?Key References:

Comprehensive and Detailed Step-by-Step Explanation:

To find how muchmentholis needed:

(0.25100)×600g=1.5g=1500mg\left( \frac{0.25}{100} \right) \times 600 g = 1.5 g = 1500 mg(1000.25​)×600g=1.5g=1500mg

📌Explanation of Answer Choices:✅C. 1500 mg→Correct.0.25% of 600 g = 1500 mg.❌A. 15 mg→ Incorrect.Calculation error.❌B. 150 mg→ Incorrect.Incorrect decimal placement.❌D. 15 g→ Incorrect.Overestimated.

📌Reference:

USP <795>: Pharmaceutical Compounding – Nonsterile Preparations

PTCB Exam: Pharmaceutical Calculations

Comprehensive and Detailed Step-by-Step Explanation:

The FDA requires patient package inserts (PPIs) for certain medications, including oral contraceptives like norethindrone/ethinyl estradiol.

📌Explanation of Answer Choices:

✅B. Norethindrone/Ethinyl Estradiol → Correct. Oral contraceptives must include a PPI with risk information.

❌A. Sulfamethoxazole/Trimethoprim → Incorrect. Does not require a package insert.

❌C. Triamterene/HCTZ → Incorrect. A diuretic, no required PPI.

❌D. Emtricitabine/Tenofovir Disoproxil → Incorrect. A PPI is required only for certain formulations.

📌Reference:

FDA Patient Information Leaflet Requirements

Comprehensive and Detailed Step-by-Step Explanation:

Procardiais thebrand name for Nifedipine, acalcium channel blocker (CCB)used totreat hypertension and angina.

📌Explanation of Answer Choices:✅A. Nifedipine→Correct.Procardia = Nifedipine.❌B. Felodipine→ Incorrect.Another CCB, but not the generic for Procardia.❌C. Diltiazem→ Incorrect.A different CCB (Cardizem).❌D. Amlodipine→ Incorrect.A CCB (Norvasc), but not the generic for Procardia.

📌Reference:

FDA Orange Book

PTCB Exam: Generic & Brand Name Medications

Risk Evaluation and Mitigation Strategies (REMS)areFDA-required programsto ensure that thebenefits of certain medications outweigh their risks. REMS programsrestrict prescribing, dispensing, and monitoringdue to the potential for serious side effects or misuse.

Suboxoneis used foropioid dependenceand containsbuprenorphine, apartial opioid agonist, which can causeaddiction, misuse, and respiratory depressionif used improperly.

REMS Requirements for Suboxone:

Prescriber Certification:Only specially certified providers can prescribe Suboxone.

Patient Education:Patients must be informed about the risks of misuse, overdose, and dependence.

Limited Dispensing:Pharmacists must ensure prescriptions meet REMS criteria before dispensing.

A. Xarelto (Rivaroxaban).→ Incorrect. While Xarelto is an anticoagulant, it isnot under REMS.

C. Warfarin.→ Incorrect. Warfarin requires monitoring butdoes not have a REMS program.

D. Haloperidol.→ Incorrect. Haloperidol is an antipsychotic, but itdoes not have a REMS program.

FDA REMS Program List (www.accessdata.fda.gov).

Suboxone REMS Guidelines (www.suboxonerems.com).

PTCB PTCE Exam Content Outline – REMS and Medication Safety.

Mosby’s Pharmacy Technician: Principles and Practice – REMS Regulations.

Why Is Suboxone (Buprenorphine/Naloxone) Under REMS?Why the Other Answer Choices Are Incorrect:Pharmacy Technician References:

Repatha (evolocumab) is a PCSK9 inhibitor used for lowering LDL cholesterol. One of its common side effects includes musculoskeletal pain, such as muscle aches and cramps. According to the FDA package insert for Repatha, clinical trials observed arthralgia, myalgia, and back pain as notable adverse events.

In contrast:

Requip (ropinirole) may cause dizziness or nausea.

Restasis (cyclosporine ophthalmic) causes eye irritation.

Restoril (temazepam) is associated with sedation.

Step 1: Convert pounds to kilograms

1 kg = 2.2 lbs

132 lbs ÷ 2.2 = 60 kg

Step 2: Calculate total dose

5 mg/kg × 60 kg = 300 mg

Thus, the correct answer isC. 660 mg.

📌Reference:PTCE Calculation Guide, Pediatric Dosage Calculations.