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Questions came word by
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NAPLEX Questions and Answers

Question # 1

A patient with multibacillary leprosy is on dapsone, clofazimine, and rifampin. Which of the following is true regarding the mechanism of action of the medications listed?

A.

Dapsone is bacteriostatic because of its inhibitory effects on dihydrofolate reductase

B.

Dapsone is bacteriostatic because of its inhibitory effects on myeloperoxidase

C.

Clofazimine is bactericidal by directly inhibiting bacterial DNA polymerase

D.

Rifampin is bacteriostatic by inhibiting RNA synthesis by blocking DNA-dependent RNA polymerase

E.

Rifampin is bactericidal by inhibiting RNA synthesis by blocking DNA-dependent RNA polymerase

Question # 2

A 67-year-old female presents to your clinic complaining of fatigue, diarrhea, headaches and a loss of appetite. Upon examination you find that she is having some cognitive difficulty. Laboratory results reveal: MCV: 109fL; Hgb: 9g/dL; MMA and homocystine are both elevated. Shilling test is positive.

What is the next best step in the management of this patient?

A.

Lifelong folic acid supplementation

B.

Lifelong Vitamin B12 supplementation

C.

Iron supplementation for 4-6 months

D.

Obtain a Coomb’s test

E.

Give corticosteroids and iron supplementation

Question # 3

What is the active ingredient found in the medicine Adalat?

A.

Nifedipine

B.

Adalimumab

C.

Digoxin

D.

Simvastatin

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